Comparison of various RBC indices and Glucose 6 phosphate dehydrogenase activity in patients with and without malaria

Introduction and Aim: Malaria is endemic in many parts of India. Glucose 6 phosphate dehydrogenase (G6PD) deficiency known to protect against malaria. G6PD deficient individuals afflicted with malaria when treated primaquine, the first line oxidant drug malaria, encounter adverse fatal complications due acute precipitation hemolytic anemia. There a need assess RBC indices its implications deficiency, manifestations. The aim this study was compare correlate various activity patients without find prevalence tertiary care hospital. Materials Methods: present carried out by Biochemistry Department Kasturba Medical College, Manipal 363 participants (with malaria). Mann Whitney U test Spearman’s Rank correlation were employed group differences correlation, respectively. Results: 218 cases 365 days from hospital South India an alarming incidence annuls fact that relatively low Complete blood counts red did not show any statistically significant difference between groups. No found study. Conclusion: hematological indicators or hint towards necessity tests for radical treatment as are unable predict defective enzyme activity.